Applied Physical cy 2/E

A UNIQUE PRACTICE-ORIENTED INTRODUCTION TO PHYSICAL CY ------------------------------------------------------------ Applied Physical cy explores the fundamental physico properties and processes important for understanding how drugs are transformed into usable and stable drug products that release their drug upon administration, and for understanding the different processes that the released drug may encounter on its way to its cological target prior to being eliminated by the body. Applied Physical cy begins with a review of key bioceutics concepts of drug liberation, absorption, distribution, sm, and excretion. These concepts, which describe the e of the drug in the body, set the framework for subsequent chapters that describe physico properties and processes such as states of matter, solutions, ionization, dissolution and partitioning, mass transport, complexation, and protein binding. Concepts in these chapters are important for not only understanding a drug's e in the body, but also for providing a scientific basis for rational drug formulation and usage. Other physical cy topics important to drug formulation are discussed in the chapters that follow, which describe dispersed systems, rheology, and interfacial phenomena. The book concludes with an overview of the principles of kinetics that are essential to understanding the rates at which many of the processes discussed in previous chapters occur. To facilitate learning, chapters are enhanced by Learning Objectives, Key Points, Problems, and Clinical Questions. To make the book as relevant to real-world practice as possible, this edition includes an increased number of clinical examples and applications.

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